P-001 - STIMULATORY EFFECT OF CITRUS EXTRACT ON NITRITE REDUCTION TO NITRIC OXIDE AT ACIDIC PH
Lima, M. A. S. S. (UNICAMP); BOMBASSARO, B. (UNICAMP); Ferreira, P.G. (UNICAMP); Salgado, I. e Martins, I. S. (UNICAMP-IB)
Area: P
Keyword: Citrus extract, nitric oxide, nitrite | [Abstract] |
P-002 - "THE ACTION MECHANISM OF A SERIES OF GLUCOSE LOWERING 1,2,3-TRIAZOLE GLYCONJUGATE COMPOUNDS: BIOCHEMICAL AND DOCKING STUDIES ON Α-GLUCOSIDASE"
Silva-Jr, F.P. (FIOCRUZ-IOC); Sodero, A.C.R. (FIOCRUZ); Ferreira, S.B. (UFF); Lima, E.S. (UFAM); Kaiser, C.R. (Universidade Federal do Rio de Janeiro (UFRJ)); Ferreira, V.F. (UFF)
Area: P
Keyword: Drug Design, Molecular Modeling, Enzymatic inhibitors | [Abstract] |
P-003 - COMPARISON BETWEEN FLAVONOID AND METAL-FLAVONOID COMPLEXES ON BINDING WITH SERUM ALBUMIN
Borges, V.F. (EFOA); Borges, V.F. (Escola de Engenharia da Universidade Federal de Minas Gerais); Schneedorf, J.M. (UNIFENAS)
Area: P
Keyword: albumin, antioxidant, ligand binding, metal-flavonoid | [Abstract] |
P-004 - OLIGOSACCHARIDES OF PREBIOTIC NATURE ARE ABLE TO INHIBIT THE OXIDATIVE PHOSPHORILATION CHAIN IN MITOCHONDRIA
Leite, L.N. (UNIFAL); Silva, G.P. (UNIFAL); Schneedorf, J.M. (UNIFENAS)
Area: P
Keyword: mitochondria, oligosaccharides, prebiotics | [Abstract] |
P-005 - PHARMACOLOGICAL ACTIVITY OF THE TOBACCO NITROSAMINE N-NITROSONORNICOTINE ON NICOTINIC ACETYLCHOLINE RECEPTORS
Nunes-Alves (USP-IQ); Ulrich, H. (USP-IQ); Nery, A. (USP-IQ)
Area: P
Keyword: N-nitrosonornicotine, Nicotinic Acetylcholine Receptors, Tobacco | [Abstract] |
P-006 - IN VITRO ANTICOAGULANT AND ANTIPLATELET ACTIVITIES OF A TRITERPENOID SAPONIN FROM ILEX PARAGUARIENSIS FRUITS
Tábitha Dahmer (UFRGS); Verli, H. (UFRGS-FF); Berger, M. (UFRGS-CBIOT); Guimarães, J.A. (UFRGS)
Area: P
Keyword: Anticoagulant, Antiplatelet, Factor Xa, Saponin, Thrombin | [Abstract] |
P-007 - HIV ASPARTYL PEPTIDASE INHIBITORS INTERFERE WITH CELLULAR PROLIFERATION, ULTRASTRUCTURE AND MACROPHAGE INFECTION OF LEISHMANIA AMAZONENSIS
Santos, L.O. (FIOCRUZ-IOC); Marinho, F.A. (UFRJ-IMPG); Alves, C.R. (FIOCRUZ); Altoé, EF (FIOCRUZ-IOC); Vitório, B.S. (FIOCRUZ-IOC); Britto, C. (NULL); Motta, M.C.M. (UFRJ); Branquinha, M.H. (UFRJ-IMPG); Santos, A.L.S. (UFRJ-IMPG); D´Avila, C.M. (FIOCRUZ-IOC)
Area: P
Keyword: HIV aspartyl peptisase inhibitors, Leishmania amazonensis, proteases | [Abstract] |
P-008 - ANTITUMOR EFFECTS OF RESVERATROL ON MCF-7 CELLS OCCUR THROUGH CASEIN KINASE II ACTIVITY INHIBITION
Silva, J.L. (UFRJ-ICB); Silva-Neto, M.A. (UFRJ-IBqM); Carneiro, A.B. (UFRJ-IBqM); Seixas-Costa, P. (UFRJ-INJC); Fialho, E. (UFRJ)
Area: P
Keyword: MCF-7cells, resveratrol, casein kinase II | [Abstract] |
P-009 - CARVEDILOL PROTECTS AGAINST THE MITOCHONDRIAL OXIDATIVE DAMAGE INDUCED BY CISPLATIN IN RAT KIDNEY
Carvalho Rodrigues, M. A. (USP-FCFRP); Martins, N.M. (USP-FCFRP); Santos, N.A.G. (NULL); Ferreira, D.A.S. (USP); Santos, A.C. (H2) (USP-FCFRP); Curti, C. (USP-FCFRP)
Area: P
Keyword: mitochondria, cisplatin, carvedilol, nephrotoxicity, ROS | [Abstract] |
P-010 - NONDIGESTIBLE OLIGOSACCHARIDES INHIBIT RAT LIVER MITOCHONDRIAL RESPIRATION
Silva, G.P. (UNIFAL); Leite, L.N. (UNIFAL); Brigagão, M.R.P.L. (UNIFAL); Schneedorf, J.M. (UNIFENAS)
Area: P
Keyword: mitichondria, prebiotic, oligosaccharides, respiration | [Abstract] |
P-011 - PROTEIN TYROSINE PHOSPHATASE SILENCING IN COMBINATION WITH VINCRISTINE AS A STRATEGY TO OVERCOME LEUKEMIA MALIGNANCY
Ferreira, P.A (UNICAMP); Ferreira, C.V. (UNICAMP-IB); Aoyama, H. (UNICAMP-IB)
Area: P
Keyword: low molecular weight protein tyrosine phosphatase, vincristine, leukemia | [Abstract] |
P-012 - THIORIDAZINE INDUCES CELL DEATH IN K562 LEUKEMIC CELLS BY INTRACELLULAR CA2+ OVERLOAD
Santos, M.V. (UMC); Nascimento, F.D. (UNIFESP); Gamero, E,J.P (Unifesp - EPM); Bincoletto, C. (UMC); Tersariol, I.L.S. (UMC); Rodrigues, T. (H2) (UMC)
Area: P
Keyword: Calcium, Lysosomes, Mitochondria, Thioridazine | [Abstract] |
P-013 - MECHANISM OF RIBOFLAVIN PHOTOTOXICITY BASED ON INFLAMMATION, SENESCENCE AND APOPTOSIS MARKERS: POTENTIAL APPLICATION ON PHOTODYNAMIC THERAPY
Shishido, S.M. (UNICAMP-IB); Machado, D. (UNICAMP); Silva, R.A. (H4) (UNICAMP); Souza, A.C.S. (UNICAMP-IB); Justo, G.Z. (NULL); Aoyama, H. (UNICAMP-IB); Ferreira, C.V. (UNICAMP-IB)
Area: P
Keyword: riboflavin, phototoxicity, Inflammation, senescence and apoptosis Markers, photodynamic therapy | [Abstract] |
P-014 - MILTEFOSINE INDUCES APOPTOSIS IN LEISHMANIA AMAZONENSIS
Marinho, F.A. (UFRJ-IMPG); Gonçalves, K.C.S. (UFRJ-IMPG); Oliveira, A.C. (H1) (NULL); Bellio, M. (NULL); Santos, A.L.S. (UFRJ-IMPG); D´Avila, C.M. (FIOCRUZ-IOC); Branquinha, M.H. (UFRJ-IMPG)
Area: P
Keyword: Miltefosine, Leishmania amazonensis, Apoptosis | [Abstract] |
P-015 - DISSECTION OF THE MODULATORY ROLE OF NITRIC OXIDE ON NEUTROPHIL MIGRATION REVEALS SOLUBLE GUANYLATE CYCLASE AS A THERAPEUTICAL TARGET IN SEPSIS
Barja-Fidalgo, C. (UERJ); Paula Neto, H.A. (UFRJ-IMPG); Amêndola, RS (Universidade do Estado do Rio de Janeiro); Cunha, F.Q. (USP-FMRP)
Area: P
Keyword: neutrophil migration, G-protein coupled receptor kinase, sepsis, nitric oxide, Guanylate Cyclase | [Abstract] |
P-016 - PROTEIN PROFILE OF THE STRAIN TRICHOPHYTON RUBRUM IN RESPONSE TO ANTIFUNGAL AGENTS
Pietro, R.C.L.R. (UNESP-FCFAR); Rodrigues, E.R. (UNAERP); Nogueira, N.G.P. (UNAERP); Fachin, A.L. (NULL); Fusco-Almeida, A.M. (UNAERP)
Area: P
Keyword: Trichophyton rubrum, Antifungal agents, protein | [Abstract] |
P-017 - RESVERATROL AND TEMOZOLOMIDE HAVE ADDITIVE CITOTOXIC EFFECT, INDUCED AUTOPHAGY AND ALTER THE CYCLE OF U87-MG CELLS
Filippi-Chiela, E. (UFRGS); Zamin, L.L. (UFRGS-ICBS); Salbego, C. (UFRGS-IB); Lenz, G. (UFRGS)
Area: P
Keyword: autophagy, cell cicle, resveratrol, temozolomide, gliom U87-MG | [Abstract] |
P-018 - NON-SATURABLE BINDING OF A PHARMACOLOGICAL XANTHONE COMPOUND ISOLATED FROM MANGOES
Santos, P.G. (UNIFAL); Schneedorf, J.M. (UNIFENAS); Santos, M.H. (H2) (EFOA)
Area: P
Keyword: mangiferin, ligand binding, albumin, xanthone | [Abstract] |
P-019 - IDENTIFICATION OF A POTENTIAL STRUCTURE FOR DESIGNING NEW ANTIMICROBIALS TO TREAT INFECTIONS CAUSED BY STAPHYLOCOCCUS EPIDERMIDIS
Abreu, P.A. (H1) (UFF); Lourenço, AL (UFF); Castro, H.C. (UFF)
Area: P
Keyword: Antimicrobials, Molecular Modeling, Staphylococcus | [Abstract] |
P-020 - ANTIINFLAMMATORY ACTIVITY OF THE NATURAL PRODUCT LAPACHOL AND ITS SYNTHETIC DERIVATE LQB 118 IN THE INHALED BACTERIAL LIPOPOLYSACCHARIDE (LPS)-INDUCED LUNG INFLAMMATION MODEL
Riça, I.G. (UFRJ); Urquiaga, B. O. (Instituto de Bioquímica Médica, UFRJ); Netto, C.D. (UFRJ); da Silva, A.J.M. (NULL); Costa, P.R.R. (NULL); Zingali, R.B. (UFRJ-IBqM); Cavalcante, M.C.M. (UFRJ-IBqM)
Area: P
Keyword: Inflammation, LPS, Lapachol, TNF-alpha | [Abstract] |
P-021 - ANTITUMORAL EFFECT OF N(4)-TOLYL-2-ACETYLPYRIDINE DERIVED THIOSEMICARBAZONES AND THEIR GALLIUM (III) COMPLEXES AGAINST GLIOMA TUMORS
Vilas-Boas, F.A.S. (CNEN-CDTN-MG); Beraldo H (UFMG); Mendes, I.M.C. (UFMG); Gouvêa dos Santos, R. (CNEN-CDTN-MG)
Area: P
Keyword: Chemotherapy, Gallium, Glioblastoma, Thiosemicarbazone | [Abstract] |
P-022 - 2-ACETYLPIRIDINE -DERIVED THIOSEMICARBAZONES: ANTITUMORAL EFFECT AGAINST MALIGNANT GLIOBLASTOMA
Soares, M.A. (H2) (CNEN-CDTN-MG); Gouvêa dos Santos, R. (CNEN-CDTN-MG); Beraldo H (UFMG); Mendes, I.M.C. (UFMG); Ornelas, P. (CNEN-CDTN-MG)
Area: P
Keyword: Thiosemicarbazones, acetylpiridine, antitumoral effect | [Abstract] |
P-023 - METABOLISM AND ACUTE TOXICITY OF THE MESOIONIC COMPOUND MI-D
Martinez, G.R. (UFPR); Romão, S. (H1) (UFPR); Cadena, S.M.S.C. (UFPR); Amorim, J.C. (UFPR); Mendez-Sanchez, S.C. (UFPR); Echevarria, A. (NULL); Silva, E.F. (H3) (UFRRJ); Rocha, M.E.M. ou Merlin, M.E. (UFPR); Noleto, G.R. (UFPR-CB); Carnieri, E.G.S. (UFPR); Oliveira, M.B.M. (UFPR)
Area: P
Keyword: mesoionic, drug metabolism, acute toxicity | [Abstract] |
P-024 - DINUCLEAR COPPER (II) COMPLEXES AS OXIDATIVE CLEAVAGE AGENTS
Fischer, F.L. (UFSC); Terenzi, H. (UFSC-CBB); Neves, A. (UFSC); Osório, R.E.H.M.B. (UFSC); Giselle Bussi (Instituto Nacional de Ciência e Tecnologia de Biologia Estru)
Area: P
Keyword: Chemical nucleases, Copper complexes, DNA cleavage | [Abstract] |
P-025 - METHYLPHENIDATE ALTERS NCS-1 EXPRESSION IN RAT BRAIN
Réus G.Z. (UNESC)
Area: P
Keyword: Methylphenidate, NCS-1, Dopamine receptor | [Abstract] |
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Abstracts