Saturday – May 17, 2008
Opening Ceremony
Paulo S.L. Beirão, President of SBBq
Sergio T. Ferreira, Chairman of PABMB
Opening Conference
Chair: Paulo Sérgio Lacerda Beirão, Instituto de Ciências Biológicas (ICB-UFMG), Brazil
The Ancestral Roots and Evolution of Brazilians
Sergio Danilo Junho Pena
Instituto de Ciências Biológicas (ICB-UFMG), Departamento de Bioquímica e Imunologia, Brazil
Sunday – May 18, 2008 - 11h30 – 12h30 – Conferences
Conference 2 - Real Room
Chair: Rafael Linden, IBCCF-UFRJ, Brazil
Neuronal Receptors of Soluble b-Amyloid Oligomers and the Mechanisms of Pathogenesis of Alzheimer's Disease
Sérgio Teixeira Ferreira, Instituto de Ciências Biomédicas (ICB-UFRJ), Dep de Bioquímica Médica, Brazil
Conference 3 - Rubi Room
Chair: Anibal E. Vercesi, Faculdade de Ciências Médicas (FCM-UNICAMP), Dep. de Patologia Clínica, Brazil
Opening New Perspectives for Brazilisan Young Scientists
Jorge Almeida Guimarães, Presidente da CAPES, Universidade Federal do Rio Grande do Sul (UFRGS), Centro de Biotecnologia, Brazil
Conference 4 - Ágata Room
Chair: Gilberto Barbosa Domont, Instituto de Química (IQ-UFRJ), Dep. de Bioquímica, Brazil
The ProteoMiner and the FortyNiners: Searching for Gold Nuggets in the Proteomic Arena Pier Giorgio Righetti, Department of Chemistry, Materials and Chemical Egineering "Giulio Natta", Polytechnic of Milano, Italy
Conference 5 - Onix Room
Chair: Arnoldo R. Façanha, Centro de Biociências e Biotecnologia (UENF-CBB), Lab de Biociências e Biotecnologia, Brazil
Root Engineering: A Strategy for Agriculture in Marginal Areas of Cultivation
Roberto A. Gaxiola, Arizona State University, School of Life Sciences, USA
Conference 6 - Topázio Room
Chair: Débora Foguel, Instituto de Ciências Biomédicas (ICB-UFRJ), Dep de Bioquímica Médica, Brazil
Fluctuation Correlation Spectroscopy in Live Cells
Enrico Gratton, University of California, Irvine, Dep of Biomedical Engineering, USA
Conference 7 - Safira Room
Chair: Gustavo H. Goldman, Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP-USP), Dep de Ciências Farmacêuticas, Brazil
Chromatin Regulated Repression and Activation of Aspergillus secondary Metabolite Gene Clusters
Nancy Pulane Keller, University of Wisconsin, Dep of Plant Pathology and Medical Microbiology and Immunology, USA
Monday – May 19, 2008 - 11h30 – 12h30 – Conferences
Conference 8 - Real Room
Chair: Alicia J. Kowaltowski, Instituto de Química (IQ-USP), Dep. de Bioquímica, Brazil
Superoxide and Age-Dependent DNA Damage
Valter D. Longo, University of Southern California, Adrus Gerontology Center, Div of Biogerentology, USA
Conference 9 - Rubi Room
Chair: Igor Polikarpov, Instituto de Física de São Carlos (IFSC-USP), Dep de Física, Brazil.
Selective Modulation of Nuclear Receptors to Attack Metabolic Syndrome and Cancer
Paul Webb, The Methodist Hospital Research Institute, Diabetes Center, Texas, USA
Conference 10 - Ágata Room
Chair: Pedro Soares de Araújo, Instituto de Química (IQ-USP), Dep de Bioquímica, Brazil
Yeast as a Model for Batten Disease: Roles for BTN1 and BTN2 in Endosome-Golgi Protein Retrieval
Jeffrey E. Gerst, Weizmann Institute Science, Dep of Molecular Genetics, Israel
Conference 11 - Onix Room
Chair: Emanuel Maltempi De Souza, Setor de Ciências Biológicas, Universidade Federal do Paraná (UFPR), Dep de Bioquímica, Brazil
Molecular Switch Mechanisms Regulating Nitrogen Fixation in Azobacter vinelandii
Ray Dixon, Dep of Molecular Microbiology, John Innes Centre, Norwic, UK
Conference 12 - Topázio Room
Chair: Walter R. Terra, Instituto de Química (IQ-USP), Dep de Bioquímica, Brazil
European Higher Education Reforms: Experience in Science and Technologies
Nuno Guimarães, Universidade de Lisboa, Faculdade de Ciências, Portugal
Conference 13 - Safira Room
Chair: Sérgio T. Ferreira, Instituto de Ciências Biomédicas (ICB-UFRJ), Dep. de Bioquímica Médica, Brazil
A Novel Regulatory Mechanism of Glycogen Metabolism is Involved in Neurodegeneration
Joan J. Guinovart, Institute for Research in Biomedicine (IRB Barcelona) and University of Barcelona. Spain
Tuesday – May 20, 2008 - 11h30 – 12h30 – Conferences
Conference 14 - Real Room
Chair: Luis O. Acerenza, Universidad de La República, Facultad de Ciencia, Instituto de Biología, Uruguay
Structural Basis of PII Signaling in Photosynthetic Organisms
Vicente Rubio, Instituto de Biomedicina de Valencia (IBV-CSIC), Spain
Conference 15 - Rubi Room
Chair: Helena C.F. de Oliveira, Instituto de Biologia, Unicamp, Brazil
RNAi Based Screens Reveal Novel Regulators of Adipose Tissue Metabolism
Adilson Guilherme, University of Massachusetts Medical School, USA
Conference 16 - Ágata Room
Chair: Lev A. Okorokov, Centro de Biociências e Biotecnologia (UENF-CBB), LFBM, Brazil
Exploiting the Pore: Regulation and Manipulation of Plant Cation Transporters
Kendal D. Hirschi, Baylor College of Medicine, Dep of Pediatrics and Human and Molecular Genetics, USA
Conference 17 - Onix Room
Chair: Ronaldo da Silva Mohana Borges, Instituto de Biofísica Carlos Chagas Filho (IBCCF-UFRJ), Brazil
Rolling with the Punch: Function and Control of Translesion Synthesis DNA Polymerases
Graham C. Walker, Massachusetts Institute of Technology – MIT, Dep of Biology, USA
Conference 18 - Topázio Room
Chair: Celia Carlini, Centro de Biotecnologia, UFRGS, Brazil
Adventures in Plant Nitrogen Metabolism: From Signaling to Defense
Joseph Polacco, Biochemistry Dep, University of Missouri-Columbia, USA
Conference 19 - Safira Room
Chair: Maria Helena Bueno Da Costa, Instituto Butantan, Centro de Biotecnologia, Brazil
Putting a Brake on Inflammation by Targeting Genes or Drugs to Endotelial Cells
Johannes A.A.M. Kamps, University of Groningen, University Medical Center Groningen (UMCG) Dep of Pathology, The Netherlands
Sunday – May 18, 2008 - 9h00 – 11h00 - Symposia
Symposium 1 – Real Room
Chair: Gloria R. Franco, Instituto de Ciências Biológicas (ICB-UFMG), Dep de Bioquímica e Imunologia, Brazil
Genome Bioinformatics
EGENE 2 - A Platform for Automated Sequence Processing and Annotation
Arthur Gruber, Faculdade de Medicina Veterinária e Zootecnia (FMVZ-USP), Dep de Patologia, Brazil
MYOP A Gene Predictor Framework
Alan M. Durham, Instituto de Matemática e Estatística (IME-USP), Dep de Ciência da Computação, Brazil
Integration and Use of Shistosoma mansoni Genomic Data for the Discovery of New Drug Targets
Guilherme C. Oliveira, Centro de Pesquisa René Rachou - MG (CPqRR-FIOCRUZ), Lab de Parasitologia Celular e Molecular, Brazil
Assembly and Annotation of Corynebacterium pseudotuberculosis Genome
Gloria R. Franco, Instituto de Ciências Biológicas (ICB-UFMG), Dep de Bioquímica e Imunologia, Brazil
Symposium 2 – Rubi Room
Chair: Marcello Iacomini, Ciências Biológicas (CB-UFPR), Dep de Bioquímica e Biologia Molecular, Brazil
Structure and Function of Carbohydrates
Pathogenic Fungi: From Polysaccharides to Glycoconjugates
Eliana Barreto-Bergter, Instituto de Microbiologia Prof. Paulo de Góes (IMPG-UFRJ), Dep de Microbiologia Geral, Brazil
Derivatization of Carbohydrates: Revised Approaches for GLC-MS Analysis
Guilherme L. Sassaki, Setor de Ciências Biológicas, Universidade Federal do Paraná (UFPR), Dep de Bioquímica, Brazil
P-Selectin as a Therapeutic Target in Thrombosis, Inflammation and Cancer: The Role of Heparin Analogues
Mauro S.G. Pavão, Hospital Universitário Clementino Fraga Filho (HUCFF-UFRJ), Brazil
Symposium 3 – Ágata Room
Chair: Leda Quercia Vieira, Instituto de Ciências Biológicas (ICB-UFMG), Dep de Bioquímica e Imunologia, Brazil
Fórum das Pós-Graduações em Bioquímica (Portuguese)
Adalberto R. Vieyra
UFRJ
Rodolfo Jardim de Azevedo
Instituto de Computação da Unicamp
Symposium 4 – Onix Room
Chair: Glaucia M. Souza, Instituto de Química (IQ-USP), Dep de Bioquimica, Brazil
Plant Biotechnology
Studies of Stress Responses in Arabidopsis thaliana and Fruits
Ariel Alejandro Lopez Orellana, Millenium Nucleus in Plant Cell Biotechnology, Center of Plant Biotechnology, Andres Bello University, Chile
Sugarcane Genomics: Gene Discovery for an Energy Grass
Glaucia M. Souza, Instituto de Química (IQ-USP), Dep de Bioquimica, Brazil
Effect of Probiotics in Prevention of Infection: From Animal Models to Clinical Trials in Brazil
Leda Q. Vieira, Instituto de Ciências Biológicas (ICB-UFMG), Dep de Bioquímica e Imunologia, Brazil
Algal Sulfated Galactans as New Antithrombotic Compounds
Paulo A.S. Mourão, Hospital Universitário Clementino Fraga Filho (HUCFF-UFRJ), Dep de Bioquímica Médica, Brazil
Symposium 5 – Topázio Room
Chair: Nuno C. Santos, Instituto de Medicina Molecular, Universidade de Lisboa, Portugal.
Biochemical Mechanisms of Viral Fusion and Assembly
Flow Cytometry Studies of the HIV-Envelope Mediated Cell-Cell Fusion
Leonor Huerta, Dep of Immunology, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Distrito Federal, México
Role of Ca2+ in Rotavirus Entry and Assembly in Cultured Cells
Marie Christine Ruiz, Lab de Fisiología Gastrointestinal, Centro de Biofísica y Bioquímica, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Venezuela
Viral Inactivation Based on Inhibition of Membrane Fusion: Understanding the Role of Histidine Protonation to Develop New Viral Vaccines
Andrea T. Da Poian, Programa de Biologia Estrutural, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Brazil
Role of the Cytoplasmic Domain of the Lentiviral Envelope Glycoproteins in Membrane Fusion and Envelope Incorporation Into Virirons
José L. Affranchino, Lab de Virología, Facultad de Ciencias Exactas y Naturales, Universidad de Belgrano, Buenos Aires, Argentina
Symposium 6 – Safira Room
Chair: Frederico Gueiros, Instituto de Química, Universidade de São Paulo, Dep de Bioquímica, Brazil
SBBq-PABMB Cone Sul Symposium
Role of the RcsC/YojN/RcsB Regulatory System in LPS Modification in Salmonella typhimurium
Monica A. Delgado, Universidad Nacional de Tucuman, INSIBIO, Argentina
Alkyl Hydroperoxide Reductase E from Mycobacterium Tuberculosis: Oxidation and Overoxidation by Hydrogen Peroxide and Peroxynitrite
Martin Hugo, Universidad de La República, Uruguay
Unfolded Protein response (UPR) Activation during Leishmania Infection
Vitor R. Pastro, InCor-HC-FM, Universidade de São Paulo, Brazil
Henotypic and Genotypic Diversity of Moraxella Spp. Strains Obtained from Infectious Bovine Keratoconjunctivitis Outbreaks in Uruguay
Vanessa Sosa, Instituto de Investigaciones Biologicas Clemente Estable, Uruguay
Experimental Effects of the Probiotic Yeast Saccharomyces boulardii on Salmonella typhimurium Infection and Signalling Pathways in T84 Cells
Flaviano dos S. Martins, Universidade Federal de Minas Gerais, Brazil
Sunday – May 18, 2008 - 14h00 – 16h00 - Symposia
Symposium 7 – Real Room
Chair: Carlos A.S.Gonçalves, Instituto de Ciências Básicas da Saúde (ICBS-UFRGS), Dep de Bioquímica, Brazil
Neuroinflammation, Neurodegenerative Disease and Neuroprotection
Molecular Mechanisms of Ethanol-Induced Neuroinflammation: Role of Glial Cells and Il-1-Ri/Tlr4 Receptors
Consuelo Guerra, Centro de Investigación Principe Felipe, Valencia, Spain
Role of Chemokines and PI3kg in Mediating Leukocyte Migration into the Central Nervous System
Mauro M. Teixeira, Instituto de Ciências Biológicas (ICB-UFMG), Dep de Bioquímica e Imunologia, Brazil
Transcription Factor Max in Programmed Cell Death and Neuroprotection
Rafael Linden, Lab de Neurogenese, IBCCF-UFRJ, Rio de Janeiro, Brazil
The Guanine-Based Purinergic System as a New Target for Neuroprotection Against Glutamatergic Excitotoxicity
Diogo O.G. Souza, Instituto de Ciências Básicas da Saúde (ICBS-UFRGS), Dep de Bioquímica, Brazil
Neuroprotective Effects of Simple Organoseleno Compounds
João B.T. Rocha, Centro de Ciências Naturais e Exatas, Universidade de Santa Maria, Dep de Química, Brazil
Symposium 8 – Rubi Room
Chair: Luiz Bezerra De Carvalho Junior, Laboratório de Imunopatologia Keizo Asami (LIKA-UFPE), Dep. de Bioquímica, Brazil
Biomarkers and Biossensors
Abiotic Biosensors
Lauro Tatsuo Kubota, Instituto de Química (IQ-UNICAMP), Dep de Química Analítica, Campinas, Brazil
Semiconductor Nanoparticles: A New Class of Fluorescent Biomarkers
Beate Saegesser Santos, Centro de Ciências da Saúde (UFPE), Dep de Ciências Farmacêuticas, Recife, Brazil
Lectins as Biomarkers
Eduardo Isidoro Carneiro Beltrão, Laboratório de Imunopatologia Keizo Asami (LIKA-UFPE), Recife, Brazil
Symposium 9 – Ágata Room
Chair: Gilberto B. Domont, Instituto de Química (IQ-UFRJ), Dep de Bioquímica, Brazil
Unraveling Biological Systems by Mass Spectrometry
Snake Venomics
Juan J. Calvete, Instituto de Biomedicina de Valencia, Spain
Challenges and Perspectives in Proteins and Peptides Imaging by Mass Spectrometry
Carlos Bloch Jr, Laboratório de Espectrometria de Massa, Embrapa Recursos Genéticos e Biotecnologia, Brasília-DF, Brasil
Proteomics-Driven Cancer Biomarker Discovery in Leukemias
Luciana Pizzatti, Laboratório de Célula Tronco, Divisão de Laboratórios do CEMO, Instituto Nacional do Câncer, Rio de Janeiro, Brasil.
Peptide Fractionation for Proteomic Studies
Gabriel Padrón, Center for Genetic Engineering and Biotechnology, Havana, Cuba
Symposium 10 – Onix Room
Chair: Emanuel Maltempi De Souza, Setor de Ciências Biológicas, Universidade Federal do Paraná (UFPR), Dep de Bioquímica, Brazil
Recent Advances in Nitrogen Fixation by Endophytes
Ammonium-Induced Nitrogenase Inactivation is Regulated by PII Proteins and Amtb- Depended Membrane Sequestration of a Regulatory Enzyme in Azospirillum brasilense
Luciano F. Huergo, Setor de Ciências Biológicas, Universidade Federal do Paraná (UFPR), Dep de Bioquímica, Brazil
Plant Growth Promoting Rhizobacteria: Evaluation of Their Diversity in Different Crops of South Brazil
Luciane M.P. Passaglia, Instituto de Biociências (IB-UFRGS), Dep de Genética, Brazil
Biofertilizers for Grasses and Cereals: What Applications of this Technology Using Selected Diazotrophic Bacteria are Viable in Brazil?
Veronica M. Reis, Centro Nacional de Pesquisa de Agrobiologia (EMBRAPA), Lab Ecofisiologia Aplicada, Brazil
Plant Signaling Pathways Mediating the Association between Graminaceous Plants and Endophytic Diazotrophic Bacteria
Adriana S. Hemerly, Instituto Bioquímica Médica (IBqM-UFRJ), Lab de Biologia Molecular de Plantas, Brazil
Symposium 11 – Topázio Room
Chair: Leda Quercia Vieira, Instituto de Ciências Biológicas (ICB-UFMG), Dep. de Bioquímica e Imunologia, Brazil
XII Award in Life Sciences for Young Scientists Talent
Biochemical Effects of the Pretreatment with Vitamins E and C in Rats Submitted to Intrastriatal Hypoxanthine Administration: Perspectives to Lesch Nyhad Disease
Caren S. Bavaresco, Dep de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
Lessons Learned after Application of the Genomic Immunization Screening Protocol to Neisseria meningitidis Serogroup B
Daniel Yeri, Dep of Molecular Biology, Finaly Institute, Habana, Cuba
Membrane Fusion as a Target for Viral Inactivation and Vaccine Development
Fausto Stauffer, Lab de Biquímica de Vírus, Instituto de Bioquímica Médica (IBqM-UFRJ), Rio de Janeiro, Brazil
Lessons from Honeybee Transcriptional Profiles
Francis M. F. Nunes, Dep. Genética, FMRP-USP
The Study of Ataxia-Telangiectasia Syndrome by Using the Filamentous Fungus Aspergillus nidulans as a Model System
Iran Malavazi, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Brazil
Symposium 12 – Safira Room
Chair: Adriana R. Lopes, Instituto Butantan
SBBq-PABMB Cone Sul Symposium
Calreticulin and the Endoplasmic Reticulum in Oocytes and Eggs of the Insect Rhodnius prolixus
Isabela B. Ramos, IBCCF, Universidade Federal do Rio de Janeiro, Brazil
Transcriptomes of Ticks, Rhipicephalus (Boophilus) microplus, Fed on Resistant and Susceptible Cattle: Genes Affected by Host Immune Responses
Sandra R.C. Maruyama, FMRP, Universidade de São Paulo, Brazil
Protein Disulfide Isomerase is Involved in Redox Regulation of Nitric Oxide Output During Laminar Shear Stress in Endothelial Cells
Denise de C. Fernández, InCor-FM, Universidade de São Paulo, Brazil
Tissue and Substrate-Specific Characteristics of Mitochondrial Reactive Oxygen Species Release
Erich B. Tahara, Departamento de Bioquímica, Instituto de Química, USP, Brazil
Mitochondrial Respiratory Chain and Creatine Kinase Activities in Rat Brain after Sepsis Induced by Cecal Ligation and Perforation
Clarissa M. Comim, Universidade do Extremo Sul Catarinense, Brazil
Monday – May 19, 2008 - 9h00 – 11h00 - Symposia
Symposium 13 – Real Room
Chair: Humberto D'Muniz Pereira, Instituto de Física de São Carlos (IFSC-USP), Brazil
New Approaches in Drug Discovery and Development
The Use of Fragment-Based Screening in Drug Discovery
Anne Cleasby, Astex Therapeutics, UK
Integration of Structure-Based and Ligand-Based Approaches in Medicinal Chemistry and Drug Design
Adriano D. Andricopulo, Instituto de Física de São Carlos (IFSC-USP), Centro de Biotecnologia, Brazil
NMR in Drug Discovery and Development
José Daniel Figueroa Villar, Instituto Militar de Engenharia (IME), Dep de Química Orgânica, Brazil
Rational Design of New Symbiotic Lead Candidates for Chronic-Degenerative Disorders
Eliezer J. Barreiro, Faculdade de Farmácia (FF-UFRJ), Lab de Avaliação e Síntese de Substâncias Bioativas, Brazil
Symposium 14 – Rubi Room
Chair: Ieso de Miranda Castro, Instituto de Ciências Exatas e Biológicas (ICEB-UFOP), NUPEB, Brazil
Improvement of Fermentative Process with Industrial Purposes
Glycerol Homeostasis, a Newborn Concept in Yeast Physiology
Candida Lucas, Universidade do Minho, Dep de Biologia, Portugal
Manipulation of Bacteria to Optimize Synthesis of Bioproducts from Glycerol
Maria Julia Pettinari, Universidad de Buenos Aires, Argentina
Genomic Adaptations of Industrial Fuel Ethanol Producing Saccharomyces cerevisiae
Boris Ugarte Stambuk, Centro de Ciências Biológicas (CBB-UFSC), Dep de Bioquímica, Brazil
Biotechnology of Lignocellulosics for the Production of Second Generation Bioethanol within the Context of Biorefinery
Nei Pereira Junior, Escola de Química (EQ-UFRJ), Dep de Eng Bioquímica, Brazil
Symposium 15 – Ágata Room
Chair: Eduardo Galembeck, Instituto de Biologia (IB-UNICAMP), Dep de Bioquímica, Brazil
Homenagem aos 70 anos de Bayardo B. Torres: Relatos de Experiências em Ensino de Bioquímica (Portuguese)
How I Learnt to Prepare Graduate Students to Be Teachers
Denise Vaz De Macedo, Instituto de Biologia (IB-UNICAMP), Dep. de Bioquímica, Brazil
The EBB1 Gene: Evolution and Ecology
Manuel J. Costa, ICVS – Life and Health Sciences Research Institute, University of Minho, Portugal
Making the Teaching/Learning Process a Creative Experience: Lessons from Bayardo
Hernan Chaimovich, Instituto de Química (IQ-USP), Dep de Bioquímica, Brazil
Symposium 16 – Onix Room
Chair: Jose R. Sotelo, Instituto de Investigaciones Biologicas Clemente Estable (IIBCE), Montevideo, Uruguay
RNA Targeting and Trafficking
Two Different Possible Origins for Axonal RNA: a) Transport from the Neuronal Soma and b) Transference to Axons from Surrounding Glia
Jose R. Sotelo, Instituto de Investigaciones Biológicas Clemente Estable, (IIBCE), Dep Proteins & Nucleic Acids, Montevideo, Uruguay
Myosin-Va Mediates RNA Localization in Primary Fibroblasts from Multiple Organs
John A. Mercer, McLaughlin Research Institute, Dep of Microbiology, USA
Targeted mRNA Trafficking and Its Role in Protein Localization and Cell Growth in Yeast
Jeffrey E. Gerst, Weizmann Institute Science, Dep of Molecular Genetics, Israel
Ribosome Transfer from Schwann Cells to Axons in the Peripheral Nervous System
Felipe A. Court, Dep of Physiological Sciences, Faculty of Biology, Universidad Catolica de Chile
Symposium 17 – Topázio Room
Chair: Fatima Dias Costa, UFBa
SBBq-PABMB Cone Sul Symposium
Evidence that 3-Hydroxyisobutyric Acid Inhibits Key Enzymes of Energy Metabolism in Cerebral Cortex of Young Rats
Carolina M. Viegas, ICBS, Universidade Federal do Rio Grande do Sul, Brazil
Mitochondrial ATP-Sensitive K+ Channels are Activated by Reactive Oxygen and Nitrogen Species
Bruno B. Queliconi, Instituto de Química, Universidade de São Paulo, Brazil
Mitochondria are Capable of Manganese-Porphyrin Reduction and Catalytically Decompose Peroxynitrite
Valeria Valez, Universidad de La Republica, Uruguay
CIS-4-Decenoic Acid Promotes Non-Selective Inner Mitochondrial Membrane Permeabilization
Patrícia F. Schuck, Universidade Federal do Rio Grande do Sul, Brazil
Deficiency of Arabidopsis thaliana Alters Activity of Mitochondrial Fe-S Proteins and Induces Oxidative Stress
Maria V. Maliandi, IIB-INTECH, Universidad de San Martin, Argentina
Symposium 18 – Safira Room
Chair: Carlos A.S. Gonçalves, UFRGS, Brazil
SBBq-PABMB Cone Sul Symposium
Study of the cAMP-Linked Pathways during Human Sperm Acrosome Reaction
Maria T. Branham, Universidad Nacional de Cuyo, Argentina
SIX3 Mutations in Holoprosencephaly (HPE) are Loss-of-Function Alleles
Sabina Domene, Argentina
Increased Oxidative Stress in the Rat Hippocampus after Ouabain Injection: Implications as an Model of Mania
Samira S. Valvassori, Universidade do Extremo Sul Catarinense, Brazil
Amyloid Aggregates Induce an Inflamatory Response
Estefania P.C. Azevedo, IBqM, Universidade Federal do Rio de Janeiro, Brazil
Dissecting Msx1 Gene Promoter
Renata B. Gomes, Instituto Nacional do Cancer
Monday – May 19, 2008 - 14h00 – 16h00 – Symposia
Symposium 19 – Real Room
Chair: Francisco R.M. Laurindo, Instituto do Coração do Hospital das Clínicas (INCOR-FM-USP), Lab. Biologia Vascular, Brazil
Aging, Senescene and Redox State
Diffusion and Cytotoxicity of Macrophage-Derived Oxidants
Maria Noel Alvarez, Facultad de Medicina, UDELAR, Montevideo, Uruguay
The Premature Ageing Syndrome Protein Cockayne Syndrome B Modulates the Repair of Oxidative DNA Lesions
Nadja Cristina De Souza Pinto, Instituto de Química (IQ-USP), Dep de Bioquímica, Brazil
Oxidative Stress and Respiratory Mitochondrial Function in Coenzyme Q Mutants
Mario Henrique de Barros, Instituto de Ciências Biomédicas I (ICB1-USP), Dep de Microbiologia, Brazil
Can Crocodilians and Vampire Bats Give us Lessons About Aging?
Marcelo Hermes Lima, Instituto de Ciências Biológicas (ICB-UnB), Dep de Biologia Celular, Brazil
Symposium 20 – Rubi Room
Chair: Igor Polikarpov, Instituto de Física de São Carlos (IFSC-USP), Dep de Física, Brazil
Structure, Dynamics and Function of Nuclear Receptors
New Insights into the Transcriptional Activity of Glucocorticoid Receptors
Eduardo Arzt, Laboratorio de Fisiologia y Biologia Molecular, FCEN-UBA e IFYBINE-CONICET, Buenos Aires Argentina
Nuclear Receptors and Sensitivity to Insulin under Obesity Conditions
Mario Saad, Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Dep de Clínica Médica.
Molecular Mechanisms of Nuclear Receptors Recognition: TR, PPARg and NGFI-B
Igor Polikarpov, Instituto de Física de São Carlos (IFSC-USP), Dep de Física, Brazil
Ligand Dissociation Pathways from Nuclear Estrogen Receptor Ligand Binding Domain through Molecular Dynamics Simulation
Milton Taidi Sonoda, Instituto de Física de São Carlos (IFSC-USP), Grupo de Cristalografia, Brazil
Symposium 21 – Ágata Room
Chair: Renato de Azevedo Moreira, Universidade de Fortaleza (Unifor), Brazil
Biochemistry and Molecular Biology of Plants
Systems Biology and Functional Genomics to understand the Molecular Mechanisms of the Nitrogen Response in Arabidopsis thaliana
Rodrigo A. Gutiérrez, Pontificia Universidad Catolica de Chile (PUC), Dep de Genética Molecular y Microbiologia, Chile
Nitric Oxide is a Versatile Signal Molecule that Possesses Multiple Targets in Plants.
Lorenzo Lamattina, Universidad de Mar del Plata-Facultad de Ciências Exactas y Naturales, Instituto de Investigaciones Biológicas (IIB), Argentina
Are Lectins and Cell Wall Polysaccharides Partners in the Cell Physiology?
Renato de Azevedo Moreira, Universidade Federal do Ceará (UFC), Dep de Bioquímica e Biologia Molecular, Brazil
Symposium 22 – Onix Room
Chair: Leonor Cancela, University of Algarve, Portugal
Skeletal Formation - Mineralization during Vertebrate Development
Fish as a Model Organism to Study Skeletal Development and Associated Pathologies
Paulo Gavaia, Universidade do Algarve, Centro de Ciências do Mar do Algarve, Faro, Portugal
Factors that Impact Skeletal Development and Skeletal Deformities in Zebrafish and Other Teleost Fish that are Used as Models in Biomedical Research
P. Eckhard Witten, Akvaforsk Institute of Aquaculture Research, Sunndalsora, Norway
How Is Time Controlled During Vertebrate Embryo Skeletal Development?
Isabel Palmeirim, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Portugal
Symposium 23– Topázio Room
Chair: Leila M. Beltramini, Instituto de Física de São Carlos (IFSC-USP), Dep de Física e Informatica, Brazil
Modernizing Biochemistry Teaching: Traditional x Virtual x E-Learning
Teaching Biochemistry in the 21st Century: Stimulating Student Learning by Combining Online Activities with Classical Lecture-Style Instruction
Duane W. Sears, University of California, Dep Mol Cell & Dev Biol, USA
Combining Lectures with Webpage Support and Independent Study
Angel Herráez Sánchez, Universidad de Acalá, Dep de Bioquimica y Biologia Molecular, Spain
Teaching Molecular Life Sciences in Large Auditoriums
Manuel J. Costa, Universidade do Minho, Escola de Ciências da Saúde, Portugal
Contemporary Science Topics Applied to Biotechnology: DVD Lectures used in Undergraduate Classes in Large Countries
Ana Lúcia P. Freitas, Universidade Federal do Ceará (UFC), Dep Bioquímica da Fortaleza, Brazil
Symposium 24 – Safira Room
Chair: Clovis Nakaie, Universidade Federal de São Paulo (Unifesp-EPM), Brazil
SBBq-PABMB Cone Sul Symposium
Biodegradation of Hydrocarbons and a New Optic Analysis for Chemotactic Response in Bacteria
Silvia E. Murialdo, Universidad Nacional de La Plata, Argentina
Novel Bioactive Peptides from the Venom and Mucous from the Brazilian Stingray Potamotrygon gr
Katia da Conceição, Instituto Burantan
Chloroplast-Generated Reactive Oxygen Species Contribute Decisively to Localised Cell Death during a Plant-Microorganism Nonhost Interaction
Matias D. Zenbriggen, Universidad Nacional de Rosario, Argentina
Expression of Two Different Sulfated Fucans by Females of Lytechinus Variegatus May Regulate the Seasonal Variation in the Fertilization of the Sea Urchin
Leonardo P. Cinelli, HUCFF, Universidade Federal do Rio de Janeiro, Brazil
IL-10 and IFN-g Modulate Fractalkine Receptor (CX3CR1) Expression on Monocytes through PI3K Pathway
Maria V. Ramos, Academia Nacional de Medicina, Argentina
Tuesday – May 20, 2008 - 9h00 – 11h00 - Symposia
Symposium 25 – Real Room
Chair: Fábio Siviero, Instituto de Ciências Biomédicas I (ICB1-USP), Dep de Biologia Celular e Desenvolvimento, Brazil
Insect Puzzles
How to be the Right Size - Gene Expression Analysis and Gene Regulatory Network Approaches in Honey Bee Development
Klaus Hartmann Hartfelder, Faculdade de Medicina de Ribeirão Preto (FMRP-USP), Dep de Biologia Celular e Molecular e Bioagentes Patogênicos, Brazil
Neuroendocrine and Circadian Control of Postembryonic Development in the Fruit Fly, Drosophila melanogaster
John Ewer, Universidade de Valparaíso, Centro de Neurociências, Facultad de Ciências, Chile
Transposons like Selfish and Domesticated Elements in Rhynchosciara americana Genome
Paula Rezende Teixeira, Instituto de Química (IQ-USP), Dep de Bioquímica, Brazil
Symposium 26 – Rubi Room
Chair: Elis C.A. Eleutherio, Instituto de Química (IQ-UFRJ), Dep. de Bioquímica, Brazil
Toxicity and Oxidative Stress
Strategy of Transcription Regulation in Yeast Subjected to Oxidative and Cadmium Stress
Claudina Rodrigues Pousada, Instituto de Tecnologia Química e Biológica (ITQB), Universidade Nacional de Lisboa, Genomics and Stress Laboratory, Portugal
Vacuolar Compartmentation Protects Saccharomyces cerevisiae Against Cadmium Toxicity and Mutagenesis
Elis C.A. Eleutherio, Instituto de Química (IQ-UFRJ), Dep. de Bioquímica, Brazil
Defining New Cellular Mechanisms for Cadmium Detoxification and/or Tolerance in the Yeast Saccharomyces cerevisiae
Joao A.P. Henriques, Instituto de Biociências (IB-UFRGS), Dep de Biofísica, Brazil
Oxidative Stress Induced by Cadmium in Plants
Ricardo A. de Azevedo, Escola Superior de Agricultura "Luiz de Queiroz" (ESALQ-USP), Dep de Genética, Brazil
Symposium 27 – Ágata Room (Portuguese)
Chair: Adalberto R. Vieyra, Instituto de Biofísica Carlos Chagas Filho (IBCCF-UFRJ), Brazil
Homenagem aos 70 anos de Leopoldo De Meis
RNAs Não-Codificadores Humanos: Padrões de Transcrição e Potenciais Funções
Sergio Verjovski-Almeida, Instituto de Química (IQ-USP), Dep. de Bioquímica, Brazil
Paulo Sérgio Lacerda Beirão, Instituto de Ciências Biológicas (ICB-UFMG), Dep. de Bioquímica e Imunologia, Brazil
Wagner Seixas da Silva, Instituto Bioquímica Médica (IBqM-UFRJ), Brazil
Antonio Galina Filho, Instituto de Ciências Biomédicas (ICB-UFRJ), Dep. de Bioquímica Medica, Brazil
Symposium 28 – Onix Room
Chair: Ramon dos Santos El-Bachá, Instituto de Ciências da Saúde (UFBA-ICS), Dep de Biofunção, Brazil
Screeningof New Compounds with Pharmacological Activity in the Central Nervous System
Looking for New Compounds with Pharmacological Activity using Cells from the Central Nervous System
Ramon dos Santos El-Bachá, Instituto de Ciências da Saúde (UFBA-ICS), Dep. de Biofunção, Brazil
Evidence of Brain Protecting Action of Carotenoids Extracted from Shrimp Against the Effects of Ethanol: A Possible Role for Astaxanthin
Rubem C.A. Guedes, Centro de Ciências Biológicas (UFPE-CCB), Dep de Nutricão, Brazil
Secondary Metabolites from Plants Species - Rational Approach to Identify New Targets to Central Nervous System (CNS) Diseases
Vanderlan da Silva Bolzani, Instituto de Química de Araraquara (IQ-UNESP), Dep. de Química Orgânica, Brazil
Symposium 29 – Topázio Room
Chair: Fernando A. Genta, Instituto Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil
SBBq-PABMB Cone Sul Symposium
The Tansaldolase from Trypanosoma cruzi
Ana Laura Stern, Universidade Geral de San Martin, Argentina
Simulations of Cruzipain Isoforms Temperature Effects on Structural Properties of Active Sites: Molecular Dynamics
Priscilla V.Z.Capriles, Laboratorio Nacional de Computação Científica, Brazil
Structure and Mechanism Analyses of 1-Cys Peroxiredoxin Ascorbate-Peroxidase Activity
Gisele Monteiro, IB, Universidade de São Paulo, Brazil
New Insight on the Regulation of the Yeast V H+-ATPase and Ca2+ Transporters by Extracellular Glucose
Camila C. Ribeiro, Universidade Estadual do Norte Fluminense, Rio de Janeiro
A New Mechanism for the Activity Regulation of GPI-Alkaline Phosphatase: Charged Lipid Interface Affect the Enzyme Kinetic Behavior
Ana Maria S. Simão, FFCLRP, Universidade de São Paulo, Brazil
Symposium 30 – Safira Room
Chair: Russolina Zingali, Instituto de Ciências Biomédicas, UFRJ, Brazil
SBBq-PABMB Cone Sul Symposium
Phosphorylated Nuclear Myosin Va Redistributes from Speckles to Nucleoli Upon Inhibition of Transcription
Munira M. Abdel Baqui, FMRP, Universidade de São Paulo, Brazil
Characterization of Interaction between Ebola Fusion Peptide and Lipid Membranes
Mônica S. de Freitas, IBqM, Universidade Federal do Rio de Janeiro, Brazil
IHBAS: A Program for Estimating Intermolecular Hydrogen Bonds
Raquel Dias, Pontifícia Universidade Católica do Rio Grande do Sul, Brazil
Inhibition of AtMYB2 DNA-Binding by Nitric Oxide Involves Cysteine S-Nitrosylation
Viviane I. Serpa, Universidade Federal de Santa Catarina, Brazil
Structural Characterization of Yeast Prion Fibrils
Fernando L.P. Soares, IBqM, Universidade Federal do Rio de Janeiro, Brazil
Tuesday – May 20, 2008 - 14h00 – 16h00 - Symposia
Symposium 31 – Real Room
Chair: Glaucius Oliva, Instituto de Física de São Carlos (IFSC-USP), Dep de Física e Informática, Brazil
Structural Biology at the Cone Sur
Structural Biology at the Pasteur Institute of Montevideo : Protein Crystallography to Understand Bacterial Lipid Biosynthesis Regulation
Alejandro Buschiazzo, Institut Pasteur, Dep of Structural Biology and Chemistry, Uruguay
Brucella bears an Atypical Riboflavin Pathway involved in Virulence
Fernando A. Goldbaum, Instituto de Investicaiones Bioquímicas, Fundación Instituto Leloir, Lab of Structural and Molecular Immunology, Argentina
The Macromolecular Crystallography Wiggler Beamline at the Brazilian Synchrotron Light Laboratory
Beatriz Gomes Guimarães, Laboratório Nacional de Luz Síncrotron (LNLS), CeBiME, Brazil
Beyond Genomes: Assessing Protein Function Using Solution Nuclear Magnetic Ressonance
Marcius da Silva Almeida, Instituto de Bioquímica Médica (IBqM-UFRJ), Dep de Bioquímica Médica, Brazil
Symposium 32 – Rubi Room
Chair: Robson Q. Monteiro, Instituto de Bioquímica Médica (IBqM-UFRJ) , Brazil
New Molecular Targets for Cancer Treatment
NFAT Family of Transcription Factors as Oncogene and Tumor Suppressor
João Paulo de Biaso Viola, Instituto Nacional do Câncer (INCA), Divisão de Biologia Celular, Brazil
Blood Coagulation Proteins as Targets for Cancer Treatment
Robson Q. Monteiro, Instituto de Bioquímica Médica (IBqM-UFRJ) , Brazil
A Microenvironmental Perspective of Melanoma Progression and Development of Chemoresistance
Roger Chammas. Faculdade de Medicina (FM-USP), Lab de Oncologia Experimental, Brazil
Use of a Rat Glioma Cell Model System to Isolate New Molecular Targets for Human Glioblastoma
Mari C. Sogayar, Instituto de Química (IQ-USP), Dep de Bioquímica, Brazil
Symposium 33 – Ágata Room
Chair: Mauricio Da Silva Baptista, Instituto de Química (IQ-USP) Dep de Bioquímica, Brazil
Giant Vesicles in Biochemistry: Looking at Individual Membranes with Microscopes
Spreading of Bio-Adhesive Vesicles on DNA Carpets
Carlos Marques, Institut Charles Sadron, CNRS, Strasbourg, FRANCE
Photosensitization of Lipid Bilayers: Observations of GUVs by Optical Microscopy
Rosangela Itri, Instituto de Física (IF-USP), Dep de Física Aplicada, Brazil
Different Mechanisms of Membrane Destabilization Studied by Optical Microscopy of Giant Vesicles: Antimicrobial Peptides, Detergents and Lipid Phase Transition
Karin do Amaral Riske, Universidade Federal de São Paulo (UNIFESP-EPM), Dep de Biofísica, Brazil
Giant Vesicles In Electric Fields
Rumiana Dimova, Max Planck Institute of Colloids and Interfaces, Dep of Theory and Bio-Systems, Germany
Symposium 34 – Onix Room
Chair: Bayardo B. Torres, Instituto de Química (IQ-USP), Dep de Bioquímica, Brazil
Ensino Informal (Portuguese)
Genética na Praça: Genetics for All
Eliana Dessen, Instituto de Biociências, Dep de Genétia, USP, Brazil
Martha Marandino
Faculdade de Educação da USP, Brazil
Learning Outside School: Is a Single Label Enough?
Douglas Falcao
Museu de Astronomia, Rio de Janeiro, Brazil
Art and Science in the Park
Mikiya Muramatsu, Instituto de Física da USP, Brazil
Symposium 35 – Topázio Room
Chair: Paulo Sergio Lacerda Beirão, Presidente da SBBq
Política Científica: Integração na América Latina
Symposium 36 – Safira Room
Chair: Adriana S. Hemerly, UFRJ-IBqM, Rio de Janeiro, Brazil
SBBq-PABMB Cone Sul Symposium
Small but Mighty. Riboregulation in Plant-Beneficial Rhizobacteria
Claudio Valverde, Universidade Nacional de Quilmes, Argentina
Proteome Analysis of Protein Deposition in Developing Seeds and Embryogenic Cell Suspensions of Cowpea (Vigna unguiculata)
Fábio C.S. Nogueira, Universidade Federal do Ceará, Fortaleza
Determination of the Function of Lycopene b-Cyclase (lycb) Gene in Daucus carota
Lorena A. Pizarro, Universidad de Chile, Chile
Crosstalk between Jasmonic Acid and Ethylene Pathways are Mediated by the HAHB4 Transcription Factor
Pablo A. Manavella, Universidad Nacional Del Litoral, Argentina
Rhizobiales Bear an Atypical Riboflavin Biosynthetic Pathway that Would be Involved in Virulence and Symbiosis
Sebastian Klinke, Fundación Instituto Leloir, Argentina
Sunday, May 18, 2008 - 20h to 21h
Mostra de Mídia Científica
Coordenador: Eduardo Galembeck, Unicamp
Gesivaldo Santos - Unicamp e UESB
Simulação dinâmica computacional de dependência de drogas por meio de redes neurais.
José Maurício Schneedorf - Unifal
SISMA - um software para visualização de rotas metabólicas para o ensino de Bioquímica
Mário Ferreira Sarraipa - Unicamp
VIas metabólicas: quebrando a cabeça
Glicólise, Ciclo de Krebs e Ciclo de Lynen
Wania Belo Maia - UFPE
Leitura virtual do método científico
Technical Seminary
Room: 03
Sunday - 18/05/08 – 14:30 to 16:00
Ana Paula de Andrade Aukar
Assessora Científica - Eppendorf do Brasil, Dra. Genética e Melhoramento de Plantas
RealPlex e EpMotion: precisão e confiabilidade em RealTime PCR.
O método de PCR em tempo real permite que a amplificação e a detecção ocorram simultaneamente e, além disso, agrega vantagens como a utilização de sondas direcionadas que tornam o ensaio altamente específico para a estimativa da concentração de ácidos nucléicos de uma determinada amostra. Esta técnica pode ser empregada para Análises Quantitativas (RealTime): estudo do padrão de expressão gênica, monitoramento de carga viral, terapia de drogas, transgênicos (OGMs), controle de qualidade; dentre outros, e Análises Qualitativas (End Point): genotipagem e detecção de patógenos. O preparo das reações de RealTime PCR com o auxilio do epMotion tem gerado inúmeras vantagens no resultado final do ensaio, como por exemplo, minimizar o desvio entre as replicatas e reduzir os custos com reagentes, visto que o volume final da reação pode ser reduzido para até 5 uL sem comprometimento dos resultados finais obtidos.
Room: 04
Sunday – 18/05/08 – 10:00 to 12:00
Biologia Molecular
Sheila Gregório Purim, PhD
Especialista em Aplicações da Applied Biosystems do Brasil, São Paulo-SP, Brazil
High Troughput: - SNPlex - Detecção de SNP. - SOLiD - Sequenciador de nova geração
A Applied Biosystems apresenta suas novidades tecnológicas para análise de SNPs e sequenciamento de DNA em larga escala. No primeiro tema, serão apresentadas as novidades acerca da utilização do Kit SNPlex para detecção e análise de SNPs nos sequenciadores automáticos de DNA, ABI 3130 e 3730. O segundo tema abordará o princípio do método do sequenciamento automático de DNA de novíssima geração na plataforma SOLiD e suas aplicação.
Room: 04
Sunday – 18/05/08 – 8:00 to 10:00
Espectrometria de Massas
Mateus Gulart Campos, M.Sc.
Supervisor de Vendas, Proteomics and Small Molecules Division da Applied Biosystems do Brasil, São Paulo-SP, Brazil
Recentes Avanços em Instrumentação, Software e Reagentes para Proteômica e descoberta de Biomarcadores.
A Applied Biosystems apresenta suas novidades em instrumentação, software e reagentes para Proteômica e descoberta de biomarcadores. Serão apresentadas as novidades acerca da aplicação dos sistemas de espectrometria de massas 4800 Plus MALDI TOF/TOF Analyzer, sistemas híbridos triploquadrupolo - Ion Trap linear (3200 Q TRAP LC/MS/MS e 4000 Q TRAP LC/MS/MS) e o sistema híbrido quadrupolo - Tempo de Voô (QqTOF) Q STAR Elite LC/MS/MS, bem como a tecnologia de reagentes para análise quantitativa iTRAQ. Adicionalmente serão abordados avanços em aplicações específicas como pesquisa de modificações pós-traducionais e imagem por MALDI (MALDI Imaging).
Room: 05
Sunday 18/05/08 - 10h to 10h30
Tema: Marcação Não Radioativa
Glaucia Maria Machado Santelli, mestrado e doutorado em Ciências Biológicas (Biologia Genética). Departamento de Biologia Celular e do Desenvolvimento, no Instituto de Ciências Biomédicas, USP – SP.
Sunday 18/05/08 - 15h to 16h
Tema: PCR em Tempo Real
Adriana de Godoy, doutorado em Ciências dos Alimentos. Especialista de Produtos Roche (Roche Applied Science)
Sunday 18/05/08 - 16h 30 min às 18h
Tema: LightCycler® 480 High Resolution Melting Master mix for DNA methylation analysis using the methylation-sensitive high resolution melting (MSHRM)methodology.
Tomasz K. Wojdacz. Institute of Human Genetics, University of Aarhus, Aarhus, Denmark.
Room: 07
Sunday - 18/05/08 – 10:00 to 11:15
Protein Enrichment (from small scale to grams).
Allan Simpson PhD.
Head of Marketing – GE Healthcare Life Sciences
The new Trap platform toolkits address the need for flexible, reproducible preparation of protein samples. The protocols include clear guidelines and recommendations on how to prepare samples so that they are suitable for downstream protein analyses such as electrophoresis and LC-MS. HiTrap Columns complete the purification portfolio: simple operation with a syringe, pump, or chromatography system; Economical and Easy scale-up.
Room: 07
Sunday - 18/05/08 - 14:00 to 15:00
Workshop - Comparative proteomics with 2D: - Parte 1
Viola Ruddat, Ph.D.
Senior Application Scientist GE Healthcare
The use of DIGE (Difference Gel Electrophoresis) for successful Biomarker Discovery
2D electrophoresis has been used as a means for biomarker discovery for decades. Many improvements have been made in the last 30 years with respect to sample preparation, equipment for easy handling, imaging and analysis software. With DIGE, changes in abundance as small as 10% can be detected reliably. This presentation will focus on how this is accomplished and provide a number of research examples using DIGE.
Room: 04
Monday - 19/05/08 - 08:00 to 12:00
Robson Carvalho, PhD
Especialista em Aplicações da Applied Biosystems do Brasil, São Paulo-SP, Brazil
PCR em Tempo Real: soluções Applied Biosystems da extração à detecção
A Applied Biosystems apresenta seus Kits e soluções para extração de RNA e DNA, transcrição reversa e subsequente uso em PCR em tempo real. A Applied Biosystems apresentará suas novidadesno contexto do fluxo de trabalho de um experimento de PCR em tempo Real. As várias aplicações da técnica também serão abordadas, como por exemplo: estudo de expressão gênica, quantificação de alvos biológicos, quantificação de transgênicos, detecção de SNPs e detecção de Patógenos.
Room: 05
Monday - 19/05/08 - 14:00 to 16:00
DIONEX BRASIL Instrumentos Científicos Ltda
Marc Yves Chalom
Especialista de Aplicações da DIONEX Brasil, São Paulo – SP
Desde o surgimento da tecnologia da cromatografia de íons nos idos dos anos 70, várias aplicações foram incorporadas, a tecnologia que na época era empregada para determinação de ânions e cátions em matrizes simples evoluíram muito permitindo hoje determinação direta de carboidratos e aminoácidos pela técnica de amperometria integrada. Serão abordadas tecnologias inovadoras como a amperometria pulsada tridimensional e os novos desenvolvimentos em fases estacionárias para determinação de proteínas, peptídeos e ácidos nucléicos. A técnica de Cromatografia Iônica e Cromatografia Líquida acoplada ou não a um espectrômetro de massas são cada vez mais aplicadas em institutos de pesquisa em bioquímica, biologia molecular, proteoma, etc.
Room: 07
Monday - 19/05/08 - 10:00 to 10:45
Gustavo Arbex Avelar, Ph.D.
Especialista de Produto da GE Healthcare Life Sciences.
Microarray como ferramenta para análise de expressão gênica, alterações cromossômicas e micro-RNA.
A plataforma de microarray da Agilent está baseada em uma abordagem integrada, flexível e aberta voltada para genômica investigativa em diversos modelos experimentais. Os array da Agilent permitem ao pesquisador realizar análises de expressão gênica, CGH (Comparative Genomic Hybridization), miRNA além de um programa de “arrays” customizados, possibilitando o seu uso com outro material genético diferente dos oferecidos em catálogo em múltiplos formatos.
Room: 07
Monday - 19/05/08 – 14:00 to 15:00
Workshop - Comparative proteomics with 2D: - Parte 2
DIGE (Difference Gel Electrophoresis) and the DeCyder 2D software
Viola Ruddat, Ph.D.
Senior Application Scientist GE Healthcare
In order to take advantage of all features of DIGE as previously discussed, the appropriate software package is necessary. In addition, to spot detection, various normalizations, background subtraction, gel matching, and basic statistics provided by DeCyder 2D, an additional module is available. EDA (Extended Data Analysis) is able to apply common multivariate statistics to proteomics data. This presentation will discuss all of these software functions in more detail, with particular focus on the multivariate tools.
Room: 07
Monday - 19/05/08 – 15:30 to 16:15
Gustavo Arbex Avelar, Ph.D.
Especialista de Produto da GE Healthcare Life Sciences.
PCR em tempo real: validação e otimização.
Uma breve introdução à tecnologia de PCR em tempo real seguido por uma descrição dos benefícios, dos métodos e critérios de seleção para o desenho, a validação e otimização de um novo ensaio. Ensaios de validação são necessários para determinar a especificidade dos seus “primers” e das “probes”, a sensibilidade, linearidade e reprodutibilidade dos resultados. Além disso, serão abordados métodos de quantificação e a adequação dos normalizadores gênicos.
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