Area: Drugs Actions

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 P-1 - EVALUATION OF AN ANTIOXIDANT SYSTEM IN RESPONSE TO CISPLATIN IN SACCHAROMYCES CEREVISIAE
Mariani, D. (UFRJ); Panek, A.D. (UFRJ-IQ); Eleutherio, E.C.A. (UFRJ-IQ); Pereira, M.D. (UFRJ-IQ)

Area: Drugs Actions Keywords:  Antioxidant system, Antitumor drugs, Cisplatin, Saccharomyces cerevisiae

[See Abstract]

 P-2 - NOCICEPTIVE EFFECT OF PERIPERAL POLYAMINES IN MICE
Drewes, C. C. (UFSM); Gewehr, C.C.V. (UFSM); Rubin, M.A. (); Ferreira, J. (UFSM)

Area: Drugs Actions Keywords:  Polyamines, Analgesic, Ion channels

[See Abstract]

 P-3 - ANTIBIOTIC AND THEORETICAL PROFILES OF 4-ANILINE-1H-PIRAZOLO[3,4-B]PIRIDINES AND 4-ANILINE-THIENE[2,3-B]PIRIDINES DERIVATIVES
Castro, H.C. (UFF); Ferreira, B.L.V. (UFF); Freitas, C.C. (UFF); Santos, D.O. (UFF); Bernardino, A.M.L. (UFF); Rodrigues, C.R. ()

Area: Drugs Actions Keywords:  antibiotic, compound, antimicrobial, design, S.epidermidis

[See Abstract]

 P-4 - INHIBITION OF F1FO-ATP SYNTHASE BY PHENOTHIAZINE STUDIES USING COMPUTATIONAL DOCKING METHODS
Shida, C.S. (UMC); Assis, J.M.L. (UMC); Nantes, I.L. (UMC); Rodrigues, T. (H2) (UMC)

Area: Drugs Actions Keywords:  phenothiazine, INHIBITION OF F1FO-ATP SYNTHASE, molecular docking

[See Abstract]

 P-5 - FUNCTIONAL CHARACTERIZATION OF AZOA, A NOVEL MOLECULAR DETERMINANT OF SENSITIVITY TO AZOLES IN ASPERGILLUS NIDULANS
Andrade, A.C. (H1) (EMBRAPA-Cenargen); Rouws, L. F. M. (EMBRAPA-Agrobiologia); De Waard, M. A. ()

Area: Drugs Actions Keywords:  Multidrug Resistance, Azoles, Filamentous fungi

[See Abstract]

 P-6 - NAPHTOQUINONES-DERIVATES EFFECTS ON PROTEINASES OF THE TRYPANOSOMA CRUZI EPIMASTIGOTE FORMS
Bourguignon SC (UFF); Castro, H.C. (UFF); Ferreira, V.F. (); Silva FC (UFF); Silva ACM (UFF); Santos, D.O. (UFF); Alves CR (FIOCRUZ)

Area: Drugs Actions Keywords:  Naftoquinones, Proteinases, Trypanosoma cruzi

[See Abstract]

 P-7 - SPINAL MECHANISMS OF ANTINOCICEPTIVE ACTION CAUSED BY DIPHENYL DISELENIDE
Jesse, C.R. (UFSM-CCNE); Pinto, L.G. (UFSM); Savegnago, L. (UFSM-CCNE); Rocha, J.B.T. (UFSM-CCNE); Zeni, G. (); Nogueira, C.W. (UFSM)

Area: Drugs Actions Keywords:  antinociceptive, selenium, diphenyl diselenide

[See Abstract]

 P-8 - CELLULAR UPTAKE AND CYTOTOXICITY IN VITRO AND TOXICITY IN VIVO OF DNA AND RNA INTERCALATOR ADAP
Marczi, S. (Clinical Hospital Osijek)

Area: Drugs Actions Keywords:  4,9-diazapyrenium, DNA intercalation, uptake, cytotoxicity, toxicity

[See Abstract]

 P-9 - EFFECT OF HYPUSINATION INHIBITION IN THE IN VITRO GROWTH AND DIFFERENTIATION OF LEISHMANIA AMAZONENSIS.
Souza, A.R. (USP-FMRP); Santos, F.R. (USP-FMRP); Ferraz, D.B. (USP); Costa-Neto, C.M. (USP-FMRP); Ramalho-Pinto, F.J. (USP)

Area: Drugs Actions Keywords:  GC7, hypusination, Leishmania amazonensis

[See Abstract]

 P-10 - THEORETICAL STUDIES OF THE MOLECULAR INTERACTIONS OF A PALLADACYCLE COMPOUND THAT PRESENT ANTITUMORAL ACTIVITY.
Tatiane F. Moraes (UMC)

Area: Drugs Actions Keywords:  Computational Simulation, quantum calculations, routes of hydrolysis

[See Abstract]

 P-11 - NEGATIVE AND POSITIVE REGULATION OF SURVIVIN EXPRESSION BY ANTHRACYCLINES IN LEUKEMIC CELL LINES
Nestal de Moraes, G. (INCA); Prazeres, M. F. (INCA); Silva, K.L. (INCA); Maia, R.C. (INCA)

Area: Drugs Actions Keywords:  Survivin, Resistance, Leukemia, Apoptosis, Anthracyclines

[See Abstract]

 P-12 - DIFFERENCES IN ACTIVITY BETWEEN EMD 72000® AND ERBITUX® IN A431 CELLS MAY RELY ON MAPK CASCADE INHIBITION
Meira, D.D. (INCA)

Area: Drugs Actions Keywords:  MAPK, EGFr, antibodies

[See Abstract]

 P-13 - ASPARTYL PEPTIDASE INHIBITOR ACTIVITY OF HYPTIS PECTINATA ESSENTIAL OIL
Rivas A.C. (UFRJ-IMPG); Palmeira, V.F. (UFRJ-CCS); Alviano, C.S. (UFRJ-IMPG); Alviano, D.S. (UFRJ-IMPG)

Area: Drugs Actions Keywords:  essential oil, Fonsecae pedrosoi, Hyptis pectinata , Peptidases

[See Abstract]

 P-14 - PERIPHERAL INJECTION OF THE SPIDER PHONEUTRIA NIGRIVENTER VENON INDUCES NOCICEPTION IN MICE.
Gewehr, C.C.V. (UFSM); Drewes, C. C. (UFSM); Rubin, M.A. (); Gomez, M.V. (UFMG-ICB); Ferreira, J. (UFSM)

Area: Drugs Actions Keywords:  analgesic, Phoneutria, venom

[See Abstract]

 P-15 - ASSOCIATION OF QUERCETIN AND NARINGENIN IN THE PREVENTION OF ERLICH ASCITIC TUMOR IN MICECELLS IN MICE LIVER
MACHADO, H. (UFJF); Oliveira, M.G.A. (UFV); Oliveira, T.T. (); Fabres, M.H.A. (UFV); RAPHAEL KLEIN (UFV); FONSECA, C. S. (UFV)

Area: Drugs Actions Keywords:  Cancer, Ehrlich Ascitic Tumor, flavonoid

[See Abstract]

 P-16 - GROWTH INIBITION OF LEISHMANIA AMAZONENSIS BY 5-(4,5-DIIDRO-1H-IMIDAZOL-2-IL)-4-(PHENYLAMINO)TIENO [-2,3-B}PIRIDINES- SYNTETIC DERIVATES.
Santos, D.O. (UFF); Nascimento, S.B. (); Tornioni, R. (UFF); Bernardino, A.M.L. (UFF); Frugulhetti, I.C.P.P. (UFF); Bourguignon SC (UFF); Corte-Real, S. (UFF); Castro, H.C. (UFF)

Area: Drugs Actions Keywords:  Cutaneous Leishmaniosis, Amidine derivates, strategies of treatment

[See Abstract]

 P-17 - DELAYED CARDIOPROTECTION INDUCED BY A NOVEL QUINAZOLINE COMPOUND MAY BE SUSTAINED BY INDUCTION OF ANGIOGENESIS AND IMPROVEMENT OF CARDIAC ENERGY METABOLISM
Deckmann, A.C. (UNICAMP); Carazzolle, M.F. (); Pereira, G.A.G. (UNICAMP-IB); Franchini, K.G. (UNICAMP)

Area: Drugs Actions Keywords:  angiogenesis, cardioprotection, microarrays, Mus musculus, quinazolines

[See Abstract]

 P-18 - CELL WALL PROTEINS EXPRESSION OF CANDIDA ALBICANS ISOLATED FROM ORAL CAVITY OF HIV CHILD MODIFY AFTER SAQUINAVIR TREATMENT
Barbosa GM (UFRJ); Portela, M.B. (UFRJ-IMPG); Souza, I.P.R. (); Alviano, D.S. (UFRJ-IMPG); Alviano, C.S. (UFRJ-IMPG); Soares, R.M.A. (UFRJ-IMPG)

Area: Drugs Actions Keywords:  antiretroviral drugs, Candida albicans, HIV infection

[See Abstract]

 P-19 - LAPACHONE DERIVATIVES AS TRIPANOCIDAL AND LOW CITOTOXICITY AGENTS: A MOLECULAR MODELING STUDY
Souza, A.M.T. (UFF); Ferreira, V.F. (); Castro, H.C. (UFF); Jorqueira, A (UFF); Santos, D.O. (UFF); Bourguignon SC (UFF); Silva, M.N. (UFF); Souza, M.C.B.V (UFF); Araújo, H.P. (FIOCRUZ); Rodrigues, C.R. ()

Area: Drugs Actions Keywords:  chagas disease, lapachone derivatives, SAR

[See Abstract]

 P-20 - INVOLVEMENT OF K+- CHANNELS IN THE ANTINOCICEPTION CAUSED BY DIPHENYL DISELENIDE IN THE FORMALIN TEST
Pinto, L.G. (UFSM); Jesse, C.R. (UFSM-CCNE); Savegnago, L. (UFSM-CCNE); Rocha, J.B.T. (UFSM-CCNE); Zeni, G. (); Nogueira, C.W. (UFSM)

Area: Drugs Actions Keywords:  Antinociceptive, Formalin test, K channels

[See Abstract]

 P-21 - IN VITRO INHIBITORY EFFECT OF PUNICA GRANATUM FRUIT EXTRACT ON GROWTH, CELL PROTEINS AND IN PROTEINASE SECRETION OF CANDIDA ALBICANS
Cavalcante KM (UFRJ); Araújo BV (UFRJ); Mendonça-Filho, R.R. (); Soares, R.M.A. (UFRJ-IMPG)

Area: Drugs Actions Keywords:  Candida albicans, cell proteins, proteinases

[See Abstract]

 P-22 - INTEGRIN SELECTIVE LIGANDS MODULATING LEUKOCYTE ACTIVATION, MIGRATION AND DEATH.
Barja-Fidalgo, C. (UERJ); Saldanha-Gama, R.F. (UERJ-IBRAG); Moraes, J.A. (UERJ-IBRAG); Mariano-Oliveira, A. (UERJ-IBRAG); Zingali, R.B. (UFRJ-ICB); Marcinkiewicz, C. ()

Area: Drugs Actions Keywords:  integrin, cell adhesion, intracellular signaling, leukocyte, apoptosis

[See Abstract]

 P-23 - CITOTOXICITY AND CELL CYCLE EFFECTS OF AMBLYOMIN-X IN CULTURED CANCER CELLS.
Ventura, J.S (Instituto Butantan); LAPETINA DL (Insituto Butantan); Sá Jr., P.L. (); Batista, I.F.C. (Instituto Butantan); Ramos, O.H.P. (Instituto Butantan); Chudzinski-Tavassi, A.M. (Instituto Butantan)

Area: Drugs Actions Keywords:  cancer cells, cell cycle, citotoxicity, Factor Xa inhibitor

[See Abstract]

 P-24 - QUINONE CITOTOXICITY IN SACCHAROMYCES CEREVISIAE CELLS
Castro, F.A.V. (UFRJ-IQ); Guimarães, F.L.P. (UFRJ); Panek, A.D. (UFRJ-IQ); Eleutherio, E.C.A. (UFRJ-IQ); Pereira, M.D. (UFRJ-IQ)

Area: Drugs Actions Keywords:  Glutathione, Glutathione transferase, Quinones, Reactive Oxygen Species, Saccharomyces cerevisiae

[See Abstract]

 P-25 - CONTROL OF LESIONS IN TNFRP55-/- MICE INFECTED WITH LEISHMANIA MAJOR MAY BE PARTIALLY ACHIEVED WITH THALIDOMIDE.
Seixas, V.A.R. (UFMG); Arantes, R.M.E. (UFMG-ICB); Afonso, L.C.C. (UFOP); Vieira, L.Q. (UFMG-ICB)

Area: Drugs Actions Keywords:  Leishmania major, Thalidomide, Lesions, TNFRp55-/- mice, TNF

[See Abstract]

 P-26 - PHENOTHIAZINES-INDUCED CELL DEATH IN LEUKEMIC K562 CELLS
Santos, M.V. (UMC); Nascimento, F.D. (UNIFESP); Bincoletto, C. (UMC); Nantes, I.L. (UMC); Rodrigues, T. (H2) (UMC); Tersariol, I.L.S. (UMC)

Area: Drugs Actions Keywords:  cell death, lysosomes, phenothiazines

[See Abstract]

 P-27 - EFFECTS OF FLAVONOIDS ON THE ACTIVITY OF PROTEINS INVOLVED IN APOPTOSIS
Soares, V. C. G. (UNESP-FCFAR); Raddi, M.S.G. (Faculdade de Ciências Farmacêuticas de Araraquara); Soares, C. P. (Universidade Estadual Paulista Júlio de Mesquita Filho)

Area: Drugs Actions Keywords:  Apoptosis, Bcl-2 protein, Flavonoids

[See Abstract]

 P-28 - A NEW EUROPIUM COMPLEX – PROMISING CHEMICAL NUCLEASE
Camargo, M. A. (UFSC); Neves, A. (UFSC); Bortoluzzi, A.J. (UFSC); Terenzi, H. (UFSC-CBB); Severino, P.C. (); Fischer, F.L. (UFSC)

Area: Drugs Actions Keywords:  Eu(III) complex, hydrolytic cleavage, nuclease

[See Abstract]

 P-29 - ATORVASTATIN INTERFERES WITH C57BL/6 MICE RESISTANCE AGAINST LEISHMANIA MAJOR
Ferraz, F. O. (UFMG); Lemos, L.V. M. (UFMG); QUEIROZ, M. F. T. (UFMG); DINIZ, M. A. D (UFMG); Santos, L.A.V.D.R. (UFMG-ICB); Santiago, H.C. (UFMG); Teixeira, M.M. (UFMG-ICB); Vieira, L.Q. (UFMG-ICB)

Area: Drugs Actions Keywords:  atorvastatin, Leishmania major, immunomodulation

[See Abstract]

 P-30 - ANTICOAGULANT AND ANTIPLATELET PROPERTIES OF KALANCHOE BRASILIENSIS
Coriolano, E.O. (UFRJ-CCS); Fratane, F.S. (UFRJ-IBqM); Assafim, M.I.D.A. (UFRJ-IBqM); Chaves, D. S. A. (UFRJ-CCS); Costa, S. S. (UFRJ-CCS); Koatz, V. (); Zingali, R.B. (UFRJ-ICB)

Area: Drugs Actions Keywords:  anticoagulant, antiplatelet, Kalanchoe brasiliensis

[See Abstract]

 P-31 - LIPID MEMBRANES HAVE A ROLE IN THE MECHANISM OF ACTION OF HIV FUSION INHIBITORS T-20 AND T-1249
Castanho, M.A.R.B. (FC-UL); Nuno C. Santos (Instituto de Medicina Molecular)

Area: Drugs Actions Keywords:  Aids, Binding, Fluorescence, Peptide

[See Abstract]

 P-32 - SIMULTANEOS INHIBITION OF GSH AND SURVIVIN OVERCOME RESISTANCE TO ARSENIC IN CANCER CELLS
Ferreira, A.C.S. (INCA); Vasconcelos, F.C. (INCA); Silva, K.L. (INCA); Maia, R.C. (INCA); Kwee, J.K. (INCA)

Area: Drugs Actions Keywords:  Arsenic Trioxide, Glutathione, Reactive Oxygen Species, Survivin

[See Abstract]

 P-33 - INHIBITION OF ENZYMATIC ACTIVITY OF PLA2 FROM C. ADAMANTEUS BY THE USE OF DIPYRONE AND PMP
Silva, S.L. (UFAM); Calgarotto, A. K. (UNICAMP); Maso, V. (UNICAMP); Damico, D.C.S. (UNICAMP-IB); Comar Jr., M. (UFAM); Oliveira, K.M.T. (UFAM); Marangoni, S. (UNICAMP-IB)

Area: Drugs Actions Keywords:  PLA2, Dipyrone, Pyrazolones

[See Abstract]

 P-34 - EFFECT OF A-TOMATINE AND TOMATIDINE ON PHYTOMONAS SERPENS
Medina, J.M. (UFRJ-IBqM); Rodrigues, J.C.F. (UFRJ-IBCCF); de Souza, W. (UFRJ-IBCCF); Moreira, O.C. (UFRJ-IBqM); Atella, G.C. (UFRJ-ICB); Barrabin, H. (UFRJ-IBqM)

Area: Drugs Actions Keywords:  Phytomonas serpens, Tomatidine, Tomatine

[See Abstract]

 P-35 - EFFECT OF EUPAFOLIN ON MONOPHENOLASE ACTIVITY
Laranjeira, F.P. (UFPR); Rocha, M.E.M. ou Merlin, M.E. (UFPR); Martinez, G.R. (UFPR); Herrerias,T. (UFPR-CB); Oliveira, M.B.M. (UFPR); Carnieri, E.G.S. (UFPR); Noleto, G.R. (UFPR-CB); Cadena, S.M.S.C. (UFPR)

Area: Drugs Actions Keywords:  flavonoid, monophenolase, tyrosinase

[See Abstract]

 P-36 - IN VIVO ANTIMALARIAL EFFECT OF RHEEDIA LONGIFOLIA PLANCH & TRIANA
Reis, P.A. (FIOCRUZ-IOC); Almeida, A.L.F. (FIOCRUZ-IOC); Nascimento, D.D. (FIOCRUZ-IOC); Broxado, A.V.A (FIOCRUZ); Bérenger, A.L.R. (FIOCRUZ-FarMan); Figueiredo, M.R. (FIOCRUZ-FarMan); Bozza, P.T. (FIOCRUZ-IOC); Castro Faria Neto, H.C.C. (FIOCRUZ-IOC); Frutuoso, V.F. (FIOCRUZ-IOC)

Area: Drugs Actions Keywords:  Antimalarial activity, Rheedia longifolia, Plasmodium berghei Anka

[See Abstract]

 P-37 - ANTITUMORAL ACTIVITY OF 2-ACETYLPYRIDINE-DERIVED THIOSEMICARBAZONES
Paulo Ornelas (CNEN-CDTN-MG); Soares, M.A. (H2) (CNEN-CDTN-MG); Mendes I M C (UFMG); Beraldo H (UFMG); Santos, R.G. (CNEN-CDTN-MG)

Area: Drugs Actions Keywords:  antitumoral activity, apoptoses, thiosemicarbazones

[See Abstract]

 P-38 - IN VITRO CYTOTOXICITY AGAINST DIFFERENT HUMAN CARCINOMA CELL LINES OF LATICIFERS PROTEINS OF CALOTROPIS PROCERA
Bezerra DP (UFC); Ramos, M.V. (UFC); Oliveira, J.S. (H2) (); Costa-Lotufo, L.V. (); Freitas CDT (Universidade Federal do Ceara); marinho-filho jdb (UFC); Moraes, M.O. (); Pessoa, C ()

Area: Drugs Actions Keywords:  anti-cancer, latex, proteins

[See Abstract]

 P-39 - EVALUATION OF FLAVONOIDS QUERCETIN AND IPRIFLAVONE EFFECTS IN CELL ADHESION OF EHRLICH ASCITIC TUMOR CELLS IN MICE LIVER
FONSECA, C. S. (UFV); MACHADO, H. (UFJF); Oliveira, M.G.A. (UFV); Oliveira, T.T. (); Fabres, M.H.A. (UFV); RAPHAEL KLEIN (UFV)

Area: Drugs Actions Keywords:  Cell adhesion, ipriflavone, quercetin, TAE

[See Abstract]

 P-40 - ANALYSIS OF PROTEIN PROFILE IN RESISTANT STRAINS OF TRICHOPHYTON RUBRUM TO ANTIFUNGAL AGENTS
Rodrigues,E.R. (UNAERP); Nogueira, N. G. P. (UNAERP); Leite, F.S. (Universidade de Ribeirão Preto); Januário, A.H. (); Fusco-Almeida, A.M. (UNAERP); Badiale, E. (Universidade de Ribeirão Preto); Fachin, A.L. (); Pietro, R.C.L.R. (UNESP-FCFAR)

Area: Drugs Actions Keywords:  Antifungal agents, resistance mechanism, Trichophyton rubrum

[See Abstract]

 P-41 - ANTINOCICEPTIVE ACTION OF SOME CYCLOPEPTIDE ALKALOIDS IN MICE
santos, G.T (UFSM); Ferreira, J. (UFSM); Morel, A.F. ()

Area: Drugs Actions Keywords:  peptides, analgesic, glutamate

[See Abstract]

 P-42 - PALLADACYCLE COMPLEX INDUCES CELL DEATH IN HUMAN LEUKEMIA CELLS
Meneghin, M.B.L (UMC); Lanetzki, C. S (Universidade Mogi das Cruzes); Barbosa, C.M.V. (); Rocha, C.O. (USP-ICB IV); Nascimento, F.D. (UNIFESP); Caires, A.C.F. (); Bincoletto, C. (UMC); Tersariol, I.L.S. (UMC)

Area: Drugs Actions Keywords:  Apoptosis, Lysosomes, Palladacycle

[See Abstract]

 P-43 - MODE OF ACTION OF THE ANTIFUNGIC ITRACONAZOLE AGAINST TOXOPLASMA GONDII TACHYZOITES IN CELL CULTURE
Érica dos Santos Martins-Duarte (UFRJ-IBCCF); de Souza, W. (UFRJ-IBCCF); Rossiane Vommaro (UFRJ)

Area: Drugs Actions Keywords:  apicomplexa, chemotherapy, endodyogeny

[See Abstract]

 P-44 - NEUTROPHILS ACTIVITY OF RATS TREATED WITH KEFIR.
Zolini, GPP (UNIFENAS); Blanco, B.A. (Universidade José do Rosário Vellano); Moreira, MEC (Universidade José do Rosário Vellano); Massoco, CO (Universidade José do Rosário Vellano); Fiorini, J.E. (UNIFENAS); Schneedorf, J.M. (UNIFENAS)

Area: Drugs Actions Keywords:  kefir, neutrophil, probiotic

[See Abstract]

 P-45 - SOLUBILIZATION AND BINDING OF A WATER-INSOLUBLE BENZOPHENONE TO ALBUMIN
Schneedorf, J.M. (UNIFENAS); Borges, V.F. (Escola de Engenharia da Universidade Federal de Minas Gerais); Brigagão, M.R.P.L. (UNIFAL)

Area: Drugs Actions Keywords:  benzophenone, binding, BSA

[See Abstract]

 P-46 - TRYPANOCIDAL ACTIVITY OF CRUDE EXTRACT OF PIPER SPECIES BY USING COLORIMETRIC METHOD AND MICROSCOPY
PASSERINI, G.D. (UNESP-FCFAR); Ambrósio, D.L. (UNESP-FCFAR); LOPES, A.A. (Universidade Estadual Paulista Júlio de Mesquita Filho); BATISTA Jr., J.M. (Universidade Estadual Paulista Júlio de Mesquita Filho); MOTA, J.S. (Universidade Estadual Paulista Júlio de Mesquita Filho); Furlan, M. (); Cicarelli, R.M.B. (UNESP-FCFAR)

Area: Drugs Actions Keywords:  Colorimetric methods, Microscopy, Piperaceae, Trypanosoma cruzi

[See Abstract]

 P-47 - EVALUATION OF NITROFURANES DERIVATIVES IN THE TRANS-SPLICING OF TRYPANOTHIONE REDUCTASE MRNA
Cicarelli, R.M.B. (UNESP-FCFAR); Okuda, E.S. (UNESP-IBILCE); Silva, M.T.A. (UNESP-FCFAR); Ambrósio, D.L. (UNESP-FCFAR)

Area: Drugs Actions Keywords:  nitrofuranes derivatives, trans-splicing, trypanotione reductase

[See Abstract]