Hypertension is a disease considered as a public health problem. In Brazil, isolated researches show that its prevalence is elevated. Among the determinant factors for blood pressure regulation is the angiotensin converting enzyme (ACE), responsible for the generation of angiotensin II, a potent vasoconstrictor. The 90 kDa isoform of ACE is a possible genetic marker of hypertension and more recently of coronary disease too. Once studies suggest different patterns in the distribution of this isoform, we are sorting out the population of Vitória – Brazil to verify the prevalence of this marker in the urine, using the Western blotting technique. A sample of 2268 subjects between 25 and 64 years old was identified at their houses in the city of Vitória and invited for clinical and laboratorial exams in the University Hospital of the Federal University of Espírito Santo. The blood pressure was measured through an auscultatory method with column of mercury. Were present at the exams 1663 subjects (73 % of the sample). The urines of part of these subjects were analyzed: 74,2 % showed 190, 90 and 65 kDa isoforms of ACE, among them 66,7 % are hypertensive; 19,4 % showed 90 and 65 kDa isoforms, 100 % are hypertensive; and 6,4 % showed 190 and 65 kDa isoforms, none is hypertensive. Among the hypertensive subjects with 190, 90 and 65 kDa isoforms of ACE, 75 % and 83,3 % have high cholesterol and triglycerides, respectively. The hypertensive subjects with 90 and 65 kDa isoforms of ACE, 66,7 % have high cholesterol and triglycerides. This preliminary analysis showed that more than 90 % of the subjects that have the 90 kDa isoform of ACE, independently of their blood pressure level, have high serum levels of cholesterol and triglycerides, what contribute raising the risk of cardiovascular problems. These data confirm the relationship of blood hypertension and the presence of 90 kDa isoform of ACE.