The aim of the present work was to evaluate a set of biological activities of aqueous extracts from Condylactis gigantea, Stichodactyla helianthus, Bunodosoma granulifera, Plexaura homomalla, Millepora alcicornis, Bartolomea annulata (Coelenterata). They included: edema induction, hemorrhage and myotoxicity, all of them in vivo, through subplantar, intradermic in the back and intramuscular in the right gastrocnemius of mice, respectively. The clotting activity was quantified by adding a measured volume of the extracts on 200µl of human plasma and recording the time up to the formation of a rigid clot. In addition, the potential of these extracts to neutralize the action of snake venom proteases was also evaluated.  The effect of the extracts upon the clotting activity of snake venoms was determined at a 1:10 and 1:30 ratio (m/m) following a pre-incubation at 37ºC for 30min. PLA₂ activity was measured in a culture medium supplemented with egg yolk (substrate) and human erytrocytes, applying the anemone extract at 10, 25 and 50µg. Extracts from Plexaura homomalla and Stichodactyla helianthus (100µg) were able to induce edema, white the other extracts did not show any effect. The hemorrhagic activity was induced only by Bunodosoma granulifera, Millepora alcicornis, Plexaura homomalla (150µg). Only Bartolomea annulata and Bunodosoma granulifera did not show any myotoxic activity, while the other extracts (50µg) induced a significant myotoxicity, the species C. gigantea and S. helianthus being more active. The PLA₂ activity was generally low, Stichodactyla helianthus, Bartolomea annulata and Plexaura homomalla being the more active. The extracts from Condylactis gigantea and Bartolomea annulata inhibited the clotting activity of B. jararacussu venom. Analysis of the proteins with Mr from 14,000 to 66,000. This work showed therefore enzymatic, pharmacological and toxic activities of these extracts, in addition to inhibitory effects upon snake venom serineproteases.